Medicinal Chemistry Unit-1st Notes PDF Free Download
In this unit we are discuss about the introduction of medicinal chemistry and history, development of medical chemistry and physiochemical properties in relaion to biological action and we will discuss about the many different types of topics like ionization, solubility, particition cofficient, hydrogen bonding, protien binding, chelation, bioisoterism, optical and Geometrical isomerism and Drug metabolism these all topics are included in unit first.
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Introduction of medicinal chemistry
- History and development of medicinal chemistry
- physiochemical properties in relation to bilogical action
- Ionization
- solubility
- partition cofficient
- hydrogen bonding
- protien binding
- chelation
- bioisoterism
- optical and geometrical isoterism
- Drug metabolism
Drug metabolism- Phase I and Phase II factor affecting drug metabolism including streo chemical aspects
