B.Pharma Medicinal Chemistry-1 Unit-3rd Handwritten Notes Free PDF Download |4th Semister|

Medicinal Chemistry-1 Unit-3rd Notes PDF Free Download

Cholinergic Neurotransmitters – Biosynthesis and catabolism  of acetylcholine , Cholinergic receptors  (Muscrinic & Nicotinic) and their distribution/ Parasympathomimeti agents SAR of Parasympathomimetic agents = Direct Acting agents – Acetylcholine , Carbachol , Bethanechol , Methacholine , Pilocarpine./Indirect Acting Agents = Cholinesterase inhibitors (Reversible & Inrreversible) – Physostigmine , Neostigmine , Pyridoxime , Edrophonium chloride , Tacrine hydrochloride , Ambenonium chloride , Isofluorphate , Echothiophate iodide , Parathione , Malathion./Cholinesterase  Reactivator =Pralidoxime  chloride / Cholinergic Blocking agents SAR of cholinolytic agents/ Solanaceous alkaloids and analogues = Atripine sulphate , Hyoscyamine sulphate , scopolamine hydrobrromide , Homatropine hydrobromide , Ipratropium bromide./ Synthetic Cholinergic blocking agents = Tropicamide , Cyclopentolate hydrochloride , clidinium bromide , dicyclomine hydrochloride , Glycopyrrolate , Methantheline bromide , Propantheline bromide , Benztropine mesylate , Orphenadrine citrate , Biperidine hydrochloride , Procylidine hydrochloride , tridihexethyl chloride , isopropamide iodide ethopropazine .

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Index of Unit -3rd [ 4th Sem ]

 

• Cholinergic Neurotransmitters –  Biosynthesis and catabolism  of acetylcholine , Cholinergic receptors  (Muscrinic & Nicotinic) and their distribution
•  Parasympathomimeti agents SAR of Parasympathomimetic agents
•   Direct Acting agents – Acetylcholine , Carbachol , Bethanechol , Methacholine , Pilocarpine.
• Indirect Acting Agents = Cholinesterase inhibitors (Reversible & Inrreversible) –Physostigmine , Neostigmine , Pyridoxime , Edrophonium chloride , Tacrine hydrochloride , Ambenonium chloride , Isofluorphate , Echothiophate iodide , Parathione , Malathion.
•  Cholinesterase  Reactivator = Pralidoxime  chloride
•   Cholinergic Blocking agents SAR of cholinolytic agents/ Solanaceous alkaloids and analogues = Atripine sulphate , Hyoscyamine sulphate , scopolamine hydrobrromide , Homatropine hydrobromide , Ipratropium bromide.
•  Synthetic Cholinergic blocking agents =  Tropicamide , Cyclopentolate hydrochloride , clidinium bromide , dicyclomine hydrochloride , Glycopyrrolate , Methantheline bromide , Propantheline bromide , Benztropine mesylate , Orphenadrine citrate , Biperidine hydrochloride , Procylidine hydrochloride , tridihexethyl chloride , isopropamide iodide ethopropazine .

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